-----Original Message-----
From: Agency for Healthcare Research and Quality (AHRQ)
Sent: 12/21/2011 10:22:24 PM
To: guyperea@live.com
Subject: Effective Health Care Program Update: New AHRQ Report Compares Newer, Older Medications for Epilepsy
Effective Health Care Program Update: New AHRQ Report Compares Newer, Older Medications for Epilepsy | A new research review from the Agency for Healthcare Research and Quality (AHRQ) evaluates the evidence for newer versus older antiepileptic medications; and generic substitution of innovator antiepileptic medications. Approximately one to three percent of people in the United States will develop epilepsy over the course of their lives.
The review from AHRQ’s Effective Health Care Program found that the older drug carbamazepine had advantages in epilepsy control over newer antiepileptic medications as a class but had more adverse effects. Older drugs valproic acid and phenytoin provided similar epilepsy control as newer antiepileptic medications but there were adverse events that occurred more commonly with these older antiepileptic medications. However, these adverse events did not significantly increase the risk of withdrawals.
Download and read Comparative Effectiveness of Medications in Patients with Epilepsy. This and many other resources for evidence-based decisionmaking are available on the AHRQ’s Effective Health Care Program Web site at www.effectivehealthcare.ahrq.gov. Thank you, Effective Health Care Program
www.effectivehealthcare.ahrq.gov
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